Quetiapin ( —— )

产品货号. M10429 CAS No. 111974-69-7

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产品名称

Quetiapin
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本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder.
产品描述

Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
同义词

——
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT; mAChR; Adrenergic Receptor; Dopamine; H1 receptor
研究领域

Neurological Disease
适应症

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1.Nasrallah HA. Mol Psychiatry. 2008 Jan;13(1):27-35.

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