Quetiapin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder.

Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.

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Endocrinology/Hormones

5-HT Receptor

5-HT; mAChR; Adrenergic Receptor; Dopamine; H1 receptor

Neurological Disease

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111974-69-7

383.51

C21H25N3O2S

>98%(HPLC)

DMSO: 36 mg/mL;Water: <1 mg/mL

OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12

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(-20℃)

With Ice Pack

≥ 2 years