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Qc1
CAS No. 403718-45-6
Qc1 ( Qc 1 )
产品货号. M27692 CAS No. 403718-45-6
Qc1 是苏氨酸脱氢酶 (TDH) 抑制剂，可用于代谢疾病的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥478 | 有现货 |
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| 5MG | ￥786 | 有现货 |
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| 10MG | ￥1393 | 有现货 |
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| 25MG | ￥2333 | 有现货 |
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| 50MG | ￥3507 | 有现货 |
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| 100MG | ￥5087 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Qc1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Qc1 是苏氨酸脱氢酶 (TDH) 抑制剂，可用于代谢疾病的研究。
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产品描述Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.(In Vitro):Qc1 prevents threonine dehydrogenase from catabolizing threonine into acetyl-CoA and glycine and blocks the charging of tetrahydrofolate(THF). In ES cells, Qc1 (10 μM) increases autophagic activity.
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体外实验Qc1 (10 μM; 2~24 hours; ES cells) shows that a substantial fraction of the total LC3 protein is in the LC3-I (cytoplasmic) form. After 16 h of TDH inhibition, most LC3 is converted to the LC3-II (lipid-modified) form, indicative of increased autophagic activity.. Qc1 blocks the charging of tetrahydrofolate. Qc1 prevents threonine dehydrogenase from catabolizing threonine into acetyl-CoA and glycine.
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体内实验——
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同义词Qc 1
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体PAR-1|Apoptosis
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研究领域——
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适应症——
化学信息
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CAS Number403718-45-6
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分子量455.45
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分子式C23H16F3N3O2S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 62.5 mg/mL (137.23 mM)
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SMILESFC(F)(F)c1cccc(c1)N1C(=S)N=C2C=C(C=C[C@@H]2C1=O)C(=O)NCc1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Di Serio C, et al. Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. Basic Clin Pharmacol Toxicol. 2007 Jul;101(1):63-9.
