Pseudoprotodioscin ( —— )

产品货号. M17757 CAS No. 102115-79-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Pseudoprotodioscin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

1.拟原薯蓣皂苷具有中等的细胞毒性。
产品描述

Pseudoprotodioscin has moderate cytotoxicity.
体外实验

In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

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CAS Number

102115-79-7
分子量

1031.2
分子式

C51H82O21
纯度

>98% (HPLC)
溶解度

In Vitro:?H2O : ≥ 100 mg/mL (96.98 mM)D)
SMILES

CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7C(=C(O8)CCC(C)COC9C(C(C(C(O9)CO)O)O)O)C)C)C)CO)O)O)O
化学全称

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