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TRAM-34
CAS No. 289905-88-0
TRAM-34 ( TRAM-34; TRAM34; TRAM 34 )
产品货号. M18371 CAS No. 289905-88-0
TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥348 | 有现货 |
|
| 25MG | ￥656 | 有现货 |
|
| 50MG | ￥1199 | 有现货 |
|
| 100MG | ￥1580 | 有现货 |
|
| 200MG | ￥2049 | 有现货 |
|
| 500MG | ￥3443 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TRAM-34
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450.
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产品描述TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli, and does not block cytochrome P450.
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同义词TRAM-34; TRAM34; TRAM 34
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通路Others
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靶点Other Targets
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受体IKCa1 (KCa3.1)
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number289905-88-0
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分子量344.84
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分子式C22H17ClN2
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纯度98%
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溶解度DMSO : ≥ 3.5 mg/mL; 10.15 mM
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SMILESn1(nccc1)C(c1ccccc1)(c1ccccc1)c1c(cccc1)Cl
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化学全称1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Wulff H, et al. Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8151-6.
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