
Prunetin
CAS No. 552-59-0
Prunetin ( —— )
产品货号. M18796 CAS No. 552-59-0
Prunetin 显着降低脂多糖攻击小鼠的血清炎症细胞因子水平和死亡率。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥721 | 有现货 |
![]() ![]() |
10MG | ¥1256 | 有现货 |
![]() ![]() |
25MG | ¥2130 | 有现货 |
![]() ![]() |
100MG | 获取报价 | 有现货 |
![]() ![]() |
200MG | 获取报价 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称Prunetin
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Prunetin 显着降低脂多糖攻击小鼠的血清炎症细胞因子水平和死亡率。
-
产品描述Prunetin significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones. Prunetin significantly suppresses ATP-induced mucin secretion from cultured RTSE cells; Prunetin inhibits the production of MUC5AC mucin protein induced by EGF or PMA from NCI-H292 cells; Prunetin also inhibits the expression of MUC5AC mucin gene induced by EGF or PMA from NCI-H292 cells.
-
体外实验Prunetin inhibited LPS-induced inflammatory cytokine production and MUC5?AC expression and secretion by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体NF-κB|ERK
-
研究领域Others-Field
-
适应症——
化学信息
-
CAS Number552-59-0
-
分子量284.26
-
分子式C16H12O5
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 100 mg/mL (351.79 mM)
-
SMILESCOC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC=C(C=C3)O)O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册




关联产品
-
Pyronin Y
Pyronin Y 是一种嵌入阳离子染料,对 RNA 显示特异性。
-
(25R)-3β,17α-dihydro...
(25R)-3β,17α-二羟基-5α-螺斯坦-6-酮3-O-α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃葡萄糖苷是从百合百合的球茎中分离出来的天然产物。
-
Valpramide
丙戊酸是丙戊酸的甲酰胺衍生物,用于治疗癫痫和一些情感障碍。