Prunetin
CAS No. 552-59-0
Prunetin ( —— )
产品货号. M18796 CAS No. 552-59-0
Prunetin significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥721 | 有现货 |
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10MG | ¥1256 | 有现货 |
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25MG | ¥2130 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Prunetin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Prunetin significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide.
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产品描述Prunetin significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones. Prunetin significantly suppresses ATP-induced mucin secretion from cultured RTSE cells; Prunetin inhibits the production of MUC5AC mucin protein induced by EGF or PMA from NCI-H292 cells; Prunetin also inhibits the expression of MUC5AC mucin gene induced by EGF or PMA from NCI-H292 cells.
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同义词——
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通路Others
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靶点Other Targets
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受体NF-κB;ERK
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研究领域Others-Field
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适应症——
化学信息
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CAS Number552-59-0
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分子量284.26
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分子式C16H12O5
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纯度98%
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溶解度——
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SMILESCOC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC=C(C=C3)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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