IP7e
CAS No. 500164-74-9
IP7e ( IP 7e;IP-7e;isoxazolo-pyridinone 7e )
产品货号. M27887 CAS No. 500164-74-9
IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3208 | 有现货 |
|
10MG | ¥4771 | 有现货 |
|
25MG | ¥7655 | 有现货 |
|
50MG | ¥10368 | 有现货 |
|
100MG | ¥14013 | 有现货 |
|
500MG | ¥28026 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称IP7e
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
-
产品描述IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.(In Vivo):IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE).
-
同义词IP 7e;IP-7e;isoxazolo-pyridinone 7e
-
通路Others
-
靶点Other Targets
-
受体ACMSD
-
研究领域——
-
适应症——
化学信息
-
CAS Number500164-74-9
-
分子量390.4
-
分子式C23H22N2O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCOCCOCc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Pellicciari R, et al. α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis. J Med Chem. 2018 Feb 8;61(3):745-759.
产品手册
关联产品
-
Isethionic acid sodi...
2-Hydroxyethanesulfonate (2-Hydroxyethanesulfonic acid or isethionic acid) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group.
-
Papain
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
-
Gastrin-Releasing Pe...
Gastrin-releasing peptide is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function.