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IP7e
CAS No. 500164-74-9
IP7e ( IP 7e;IP-7e;isoxazolo-pyridinone 7e )
产品货号. M27887 CAS No. 500164-74-9
IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3208 | 有现货 |
|
| 10MG | ￥4771 | 有现货 |
|
| 25MG | ￥7655 | 有现货 |
|
| 50MG | ￥10368 | 有现货 |
|
| 100MG | ￥14013 | 有现货 |
|
| 500MG | ￥28026 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称IP7e
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
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产品描述IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.(In Vivo):IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE).
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同义词IP 7e;IP-7e;isoxazolo-pyridinone 7e
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通路Others
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靶点Other Targets
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受体ACMSD
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研究领域——
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适应症——
化学信息
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CAS Number500164-74-9
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分子量390.4
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分子式C23H22N2O4
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纯度>98% (HPLC)
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溶解度——
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SMILESCOCCOCc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Pellicciari R, et al. α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis. J Med Chem. 2018 Feb 8;61(3):745-759.
产品手册
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