Prucalopride ( Prucalopride; Prucalopride free base )

产品货号. M12708 CAS No. 179474-81-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Prucalopride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively.
产品描述

Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
同义词

Prucalopride; Prucalopride free base
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT1A; 5-HT1B; 5-HT3; 5-HT4A; 5-HT4B
研究领域

Neurological Disease
适应症

——

CAS Number

179474-81-8
分子量

367.87
分子式

C18H26ClN3O3
纯度

>98%(HPLC)
溶解度

Ethanol: 38 mg/mL (103.29 mM); DMSO: 60 mg/mL (163.1 mM)
SMILES

ClC1=CC(C(NC2CCN(CCCOC)CC2)=O)=C3C(CCO3)=C1N
化学全称

4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide

1.Briejer MR, et al. Eur J Pharmacol, 2001, 423(1), 71-83.

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