Protostemonine ( —— )

产品货号. M18348 CAS No. 27495-40-5

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Protostemonine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo.
产品描述

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM.Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.
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