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PfDHODH-IN-2

CAS No. 425629-94-3

PfDHODH-IN-2 ( —— )

产品货号. M22750 CAS No. 425629-94-3

PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1320 有现货
10MG ¥2001 有现货
25MG ¥3686 有现货
50MG ¥5443 有现货
100MG ¥7744 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PfDHODH-IN-2
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor.
  • 产品描述
    PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor .?It is used an antimalarial agent and can be used for the research of malaria.
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    PfDHODH
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    425629-94-3
  • 分子量
    297.76
  • 分子式
    C13H12ClNO3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:12 mg/mL?(40.3 mM;?Need ultrasonic)
  • SMILES
    CCOC(=O)C1=C(Nc2ccc(Cl)cc2)SCC1=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56(20):7911-24.
产品手册
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