Perlapine ( AW-14233;HF-2333;Hypnodine )

产品货号. M13091 CAS No. 1977-11-3

Perlapine (AW-14233;HF-2333;Hypnodine) is a potent antihistamine that has high affinity for dopamine D1, α1, α2 and 5-HT2A receptors.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
100MG	获取报价	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Perlapine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Perlapine (AW-14233;HF-2333;Hypnodine) is a potent antihistamine that has high affinity for dopamine D1, α1, α2 and 5-HT2A receptors.
产品描述

Perlapine (AW-14233;HF-2333;Hypnodine) is a potent antihistamine that has high affinity for dopamine D1, α1, α2 and 5-HT2A receptors with IC50 of 198, 19, 4945 and 70 nM, respectively; also has anticholinergic, antiserotonergic, antiadrenergic and antidopaminergic activity; also is a highly potent hM3Dq agonist (EC50=2.8 nM) but do not activate the native human M3 receptor (hM3, EC50>30 uM).
同义词

AW-14233;HF-2333;Hypnodine
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

——
适应症

——

化学信息

CAS Number

1977-11-3
分子量

291.40
分子式

C19H21N3
纯度

>98% (HPLC)
溶解度

——
SMILES

CN1CCN(C2=NC3=CC=CC=C3CC4=CC=CC=C42)CC1
化学全称

6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Stille G, et al. Psychopharmacologia. 1973 Feb 20;28(4):325-37.
2. Wilk S, et al. Eur J Pharmacol. 1977 Jan 7;41(1):65-72.
3. Chen X, et al. ACS Chem Neurosci. 2015 Mar 18;6(3):476-84.

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产品手册

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