Pericyazine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Pericyazine 是一种选择性 D2-多巴胺受体拮抗剂。哌啶嗪是第一代抗精神病化合物，用作严重焦虑状态和精神病的短期治疗的辅助化合物。

Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psychosis.

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Studies in rodents show that Pericyazine is able to produce potentiation of ether and hexobarbital narcosis and morphine analgesia. It also has hypothermic activity and produces depression of spontaneous motor activity in mice. On a milligram potency basis, Pericyazine is more potent than chlorpromizine in the potentiation of barbiturate narcosis test and the blocking of conditioned avoidance in rats. Pericyazine demonstrates analgesic properties similar to methotrimeprazine in mice and rats and produces adrenergic blocking effects in mice and dogs.

Propericiazine | RP 8909

GPCR/G Protein

Dopamine Receptor

D2-dopamine receptor

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2622-26-6

365.49

C21H23N3OS

>98% (HPLC)

DMSO:200 mg/mL (547.21 mM; Need ultrasonic)

N#Cc(cc1)cc2c1Sc(cccc1)c1N2CCCN(CC1)CCC1O

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(-20℃)

With Ice Pack

≥ 2 years