021-51111890
购物车（）
sales@molnova.cn
SB-277011
CAS No. 215803-78-4
SB-277011 ( SB-277011-A;SB-277011A;SB277011;SB 277011 )
产品货号. M13441 CAS No. 215803-78-4
A potent and selective dopamine D3 receptor antagonist with pKi of 8.0.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥721 | 有现货 |
|
| 10MG | ￥1150 | 有现货 |
|
| 25MG | ￥2163 | 有现货 |
|
| 50MG | ￥3605 | 有现货 |
|
| 100MG | ￥5314 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称SB-277011
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent and selective dopamine D3 receptor antagonist with pKi of 8.0.
-
产品描述A potent and selective dopamine D3 receptor antagonist with pKi of 8.0; displays >100-fold selectivity against the D2, 5-HT1B, and 5-HT1D receptors; exhibits high oral bioavailability and brain penetration in rats.Schizophrenia Discontinued
-
同义词SB-277011-A;SB-277011A;SB277011;SB 277011
-
通路GPCR/G Protein
-
靶点Dopamine Receptor
-
受体Dopamine Receptor
-
研究领域Neurological Disease
-
适应症Schizophrenia
化学信息
-
CAS Number215803-78-4
-
分子量438.56
-
分子式C28H30N4O
-
纯度>98% (HPLC)
-
溶解度10 mM in DMSO
-
SMILESC1CC(CCC1CCN2CCC3=C(C2)C=CC(=C3)C#N)NC(=O)C4=CC=NC5=CC=CC=C45
-
化学全称4-Quinolinecarboxamide, N-[trans-4-[2-(6-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Stemp G, et al. J Med Chem. 2000 May 4;43(9):1878-85.
2. Reavill C, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65.
3. Ashby CR Jr, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1166-74.
2. Reavill C, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65.
3. Ashby CR Jr, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1166-74.
产品手册
关联产品
-
Ro 10-5824 dihydroch...
Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM).
-
L-745870 trihydrochl...
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. L-745870 trihydrochloride exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors and shows weaker affinity for D2 and D3 receptors.
-
L-(-)-α-Methyldopa
Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.
