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PVZB-1194
CAS No. 1141768-04-8
PVZB-1194 ( PVZB1194 )
产品货号. M10501 CAS No. 1141768-04-8
PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称PVZB-1194
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM.
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产品描述PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM; inhibits HeLa cell proliferation with IC50 of 5.5 uM; potently inhibits KSP in a microruble dependent manner and induces a monoastral phenotype to arrest mitotic progression, abnormal KSP localization.
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同义词PVZB1194
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通路Cytoskeleton/Cell Adhesion Molecules
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靶点Kinesin
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受体Kinesin
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研究领域——
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适应症——
化学信息
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CAS Number1141768-04-8
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分子量319.27
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分子式C13H9F4NO2S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称4-[3-fluoro-4-(trifluoromethyl)phenyl]benzenesulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Matsuno K, et al. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1058-61.
2. Yokoyama H, et al. ACS Chem Biol. 2015 Apr 17;10(4):1128-36.
2. Yokoyama H, et al. ACS Chem Biol. 2015 Apr 17;10(4):1128-36.
产品手册
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