PHTPP ( PHTPP )

产品货号. M16016 CAS No. 805239-56-9

A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥308	有现货
5MG	￥494	有现货
10MG	￥753	有现货
25MG	￥1474	有现货
50MG	￥2406	有现货
100MG	￥3718	有现货
500MG	￥7995	有现货
1G	获取报价	有现货

拼团产品询价大包装询价加入购物车

生物学信息

产品名称

PHTPP
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist.
产品描述

A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist, while exhibiting no significant agonism on ERβ or Erα; enhances SKOV3 and OV2008 ovarian cancer cell growth in in vitro assays.
同义词

PHTPP
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

ERβ
研究领域

Cancer
适应症

——

化学信息

CAS Number

805239-56-9
分子量

423.30
分子式

C20H11F6N3O
纯度

>98% (HPLC)
溶解度

DMSO: 14 mg/mL (33 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

OC1=CC=C(C2=C3N=C(C(F)(F)F)C=C(C(F)(F)F)N3N=C2C4=CC=CC=C4)C=C1
化学全称

4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Compton DR, et al. J Med Chem. 2004 Nov 18;47(24):5872-93.
2. Chan KK, et al. J Endocrinol. 2014 May 12;221(2):325-36.
3. Kajta M, et al. Neuroscience. 2013 May 15;238:345-60.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

关联产品

Elacestrant dihydroc...

Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD).
Cyclofenil

Cyclofenil is an estrogen antagonist has anti-dengue-virus activity.
(E/Z)-GSK5182?

(E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers.

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks