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PF-04781340
CAS No. 1648726-56-0
PF-04781340 ( PF 04781340;PF04781340 )
产品货号. M12519 CAS No. 1648726-56-0
A potent, selective, CNS penetrant 5-HT2C receptor agonist with Ki of 3 nM and EC50 of 9 nM, without significant P-gp efflux liability.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PF-04781340
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective, CNS penetrant 5-HT2C receptor agonist with Ki of 3 nM and EC50 of 9 nM, without significant P-gp efflux liability.
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产品描述A potent, selective, CNS penetrant 5-HT2C receptor agonist with Ki of 3 nM and EC50 of 9 nM, without significant P-gp efflux liability; displays >150-fold selectivity over 5-HT2B receptors agonism (EC50=1484 nM); exhibits good metabolic stability in human liver microsomes (HLM) and moderate to good passive permeability in RRCK cells.
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同义词PF 04781340;PF04781340
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number1648726-56-0
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分子量267.38
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分子式C17H21N3
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称3-benzyl-N-methyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepin-1-amine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.
产品手册
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