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PF-03246799
CAS No. 1065110-62-4
PF-03246799 ( PF 03246799;PF03246799;PF-3246799 )
产品货号. M10282 CAS No. 1065110-62-4
A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PF-03246799
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.
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产品描述A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A; has minimal activation at either the 5-HT(2A) or 5-HT(2B) receptors, demonstrates robust efficacy in preclinical canine model of stress urinary incontinence (SUI) and attractive pharmacokinetic and safety properties.
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同义词PF 03246799;PF03246799;PF-3246799
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number1065110-62-4
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分子量239.32
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分子式C15H17N3
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纯度>98% (HPLC)
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溶解度——
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SMILESC12=NC(CC3=CC=CC=C3)=NC=C1CCNCC2
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化学全称2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Andrews MD, et al. Bioorg Med Chem Lett. 2011 May 1;21(9):2715-20.
2. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.
2. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.
产品手册
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