PF-00610355
CAS No. 862541-45-5
PF-00610355 ( PF-610355 )
产品货号. M16243 CAS No. 862541-45-5
PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥14337 | 有现货 |
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50MG | ¥28998 | 有现货 |
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100MG | ¥39690 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称PF-00610355
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.
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产品描述PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM; displays 220-fold selectivity over β1; exhibits potential as inhaled ultra-long-acting bronchodilators for the treatment of asthma and chronic obstructive pulmonary disease.Asthma Phase 2 Discontinued
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同义词PF-610355
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通路Angiogenesis
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靶点Adrenergic Receptor
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受体Adrenergic Receptor
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研究领域Inflammation/Immunology
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适应症Asthma
化学信息
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CAS Number862541-45-5
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分子量617.76
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分子式C34H39N3O6S
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(NCC1=CC(C2=CC=C(O)C=C2)=CC=C1)CC3=CC=CC(CC(C)(NC[C@H](O)C4=CC=C(O)C(NS(=O)(C)=O)=C4)C)=C3
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化学全称N-((4'-hydroxy(1,1'-biphenyl)-3-yl)methyl)-3-(2-(((2R)-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)-benzeneacetamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Glossop PA, et al. J Med Chem. 2010 Sep 23;53(18):6640-52.
2. Diderichsen PM, et al. Br J Clin Pharmacol. 2013 Nov;76(5):752-62.
2. Diderichsen PM, et al. Br J Clin Pharmacol. 2013 Nov;76(5):752-62.
产品手册
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