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PF-00610355

CAS No. 862541-45-5

PF-00610355 ( PF-610355 )

产品货号. M16243 CAS No. 862541-45-5

PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥14337 有现货
50MG ¥28998 有现货
100MG ¥39690 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PF-00610355
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.
  • 产品描述
    PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM; displays 220-fold selectivity over β1; exhibits potential as inhaled ultra-long-acting bronchodilators for the treatment of asthma and chronic obstructive pulmonary disease.Asthma Phase 2 Discontinued
  • 同义词
    PF-610355
  • 通路
    Angiogenesis
  • 靶点
    Adrenergic Receptor
  • 受体
    Adrenergic Receptor
  • 研究领域
    Inflammation/Immunology
  • 适应症
    Asthma

化学信息

  • CAS Number
    862541-45-5
  • 分子量
    617.76
  • 分子式
    C34H39N3O6S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(NCC1=CC(C2=CC=C(O)C=C2)=CC=C1)CC3=CC=CC(CC(C)(NC[C@H](O)C4=CC=C(O)C(NS(=O)(C)=O)=C4)C)=C3
  • 化学全称
    N-((4'-hydroxy(1,1'-biphenyl)-3-yl)methyl)-3-(2-(((2R)-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)-benzeneacetamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Glossop PA, et al. J Med Chem. 2010 Sep 23;53(18):6640-52.
2. Diderichsen PM, et al. Br J Clin Pharmacol. 2013 Nov;76(5):752-62.
产品手册
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