PEAQX

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PEAQX(NVP-AAM 077) 是一种有效的口服 NMDA 拮抗剂。它可以抑制人类 NMDA 受体 1A/2A (IC50: 270 nM)，而不是 1A/2B (29, 600 nM)。

PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.

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NVP-AAM077 | NVP-AAM 077 | NVP-AAM-077

Neuroscience

Gamma-secretase

hNMDA 1A/2A receptors

Neurological Disease

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459836-30-7

516.2

C17H17BrN3Na2O6P

>98% (HPLC)

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O=c1c(=O)[nH]c2c(c(C(P(=O)(O)O)N[C@H](c3ccc(Br)cc3)C)ccc2)[nH]1

sodium ((((S)-1-(4-bromophenyl)ethyl)amino)(2,3-dioxidoquinoxalin-5-yl)methyl)phosphonate hydrate .

(-20℃)

With Ice Pack

≥ 2 years