021-51111890
购物车（0）
sales@molnova.cn
Aβ-IN-1
CAS No. 2766509-32-2
Aβ-IN-1 ( —— )
产品货号. M35706 CAS No. 2766509-32-2
Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥4522 | 有现货 |
|
| 5MG | ￥6686 | 有现货 |
|
| 10MG | ￥9125 | 有现货 |
|
| 25MG | ￥12434 | 有现货 |
|
| 50MG | ￥15484 | 有现货 |
|
| 100MG | ￥19125 | 有现货 |
|
| 500MG | ￥37485 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Aβ-IN-1
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
-
产品描述Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Neuroscience
-
靶点Gamma-secretase
-
受体Gamma-secretase
-
研究领域——
-
适应症——
化学信息
-
CAS Number2766509-32-2
-
分子量483.77
-
分子式C35H49N
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESC[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C=5C(CC2)=NC=6C(C5C)=CC=CC6)[H])[H]
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
Genz-123346 free bas...
Genz 123346 是一种 GL1 合酶抑制剂，可阻止神经酰胺转化为 GL1。
-
CIA-1 (Free base)
CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenografts.
-
BI-1408
BI-1408 是一种有效的 γ 分泌酶调节剂，作用于 Aβ42 的 IC50 为 0.04 μM。
