Ogerin ( —— )

产品货号. M23467 CAS No. 1309198-71-7

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产品名称

Ogerin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice.
产品描述

Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor.
同义词

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通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT2B;A2A;GPR68
研究领域

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适应症

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1.Huang XP, et al. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature. 2015 Nov 26;527(7579):477-83.

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