Nimbolide
CAS No. 25990-37-8
Nimbolide ( —— )
产品货号. M24163 CAS No. 25990-37-8
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1847 | 有现货 |
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10MG | ¥3216 | 有现货 |
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25MG | ¥5370 | 有现货 |
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50MG | ¥7655 | 有现货 |
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100MG | ¥10368 | 有现货 |
|
500MG | ¥20817 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Nimbolide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.
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产品描述Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L).
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同义词——
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通路Apoptosis
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靶点Apoptosis
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受体Apoptosis;CDK4;CDK6;NF-κB
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研究领域——
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适应症——
化学信息
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CAS Number25990-37-8
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分子量466.5
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分子式C27H30O7
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纯度>98% (HPLC)
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溶解度——
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SMILESC[C@]12[C@@]3([H])[C@](OC([C@@]3(C=CC2=O)C)=O)([H])[C@]4([H])[C@]([C@@H]1CC(OC)=O)(C5=C(C)[C@@](C6=COC=C6)([H])C[C@@]5([H])O4)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.
产品手册
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