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Nimbolide

CAS No. 25990-37-8

Nimbolide ( —— )

产品货号. M24163 CAS No. 25990-37-8

Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1847 有现货
10MG ¥3216 有现货
25MG ¥5370 有现货
50MG ¥7655 有现货
100MG ¥10368 有现货
500MG ¥20817 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Nimbolide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.
  • 产品描述
    Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L).
  • 同义词
    ——
  • 通路
    Apoptosis
  • 靶点
    Apoptosis
  • 受体
    Apoptosis;CDK4;CDK6;NF-κB
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    25990-37-8
  • 分子量
    466.5
  • 分子式
    C27H30O7
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C[C@]12[C@@]3([H])[C@](OC([C@@]3(C=CC2=O)C)=O)([H])[C@]4([H])[C@]([C@@H]1CC(OC)=O)(C5=C(C)[C@@](C6=COC=C6)([H])C[C@@]5([H])O4)C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.
产品手册
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