
Nicotiflorin
CAS No. 17650-84-9
Nicotiflorin ( —— )
产品货号. M18129 CAS No. 17650-84-9
烟花苷对减少多发梗死痴呆模型大鼠的记忆功能障碍、能量代谢障碍和氧化应激具有保护作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1199 | 有现货 |
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10MG | ¥1758 | 有现货 |
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25MG | ¥2940 | 有现货 |
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50MG | ¥4358 | 有现货 |
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100MG | ¥6310 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Nicotiflorin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述烟花苷对减少多发梗死痴呆模型大鼠的记忆功能障碍、能量代谢障碍和氧化应激具有保护作用。
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产品描述Nicotiflorin has potential therapeutic effects on cerebral ischemic illness. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.
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体外实验For primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron. After total 4 h hypoxia and 12 h reoxygenation, eNOS activity, mRNA and protein levels in the primarily cultured rat cerebral blood vessel endothelial cells treated with nicotiflorin (25-100 g/mL) 2 h after onset of hypoxia are significantly higher than eNOS activity, mRNA and protein levels in the pure H-R cells and also higher than eNOS activity, mRNA and protein levels in cells cultured under normoxic conditions.
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体内实验At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits.
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同义词——
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通路Immunology/Inflammation
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靶点TLR
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受体Others
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number17650-84-9
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分子量594.52
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分子式C27H30O15
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (420.51 mM)
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SMILESCC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)O)O)O)O)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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