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Nacubactam
CAS No. 2007923-17-1
Nacubactam ( OP 0595;RG 6080;RO 7079901 )
产品货号. M13133 CAS No. 2007923-17-1
Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥8667 | 有现货 |
|
| 50MG | ￥17658 | 有现货 |
|
| 100MG | ￥22680 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Nacubactam
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM.
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产品描述Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM, also acts as a PBP2-active antibacterial; exhibits MICs of 0.5 to 4 μg/ml for most members of the family Enterobacteriaceae, owing to inhibition of PBP2; has MICs of 1-4 mg/ml for Escherichia coli, Enterobacter, Citrobacter and Klebsiella spp; increases the antibacterial activity of cefepime in both in vitro and in vivo.Bacterial Infection Phase 1 Clinical
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同义词OP 0595;RG 6080;RO 7079901
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number2007923-17-1
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分子量342.32
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分子式C9H18N4O8S
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纯度>98% (HPLC)
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溶解度——
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SMILESC1CC(N2CC1N(C2=O)OS(=O)(=O)O)C(=O)NOCCN.O
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化学全称(2S, 5R)-N-(2-Aminoethoxy)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, monohydrate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Morinaka A, et al. J Antimicrob Chemother. 2015 Oct;70(10):2779-86.
2. Livermore DM, et al. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.
3. Livermore DM, et al. Antimicrob Agents Chemother. 2015 Nov 9;60(1):554-60.
4. Morinaka A, et al. J Antibiot (Tokyo). 2017 Mar;70(3):246-250.
2. Livermore DM, et al. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.
3. Livermore DM, et al. Antimicrob Agents Chemother. 2015 Nov 9;60(1):554-60.
4. Morinaka A, et al. J Antibiot (Tokyo). 2017 Mar;70(3):246-250.
产品手册
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