021-51111890
购物车（0）
sales@molnova.cn
NST-628
CAS No. 3002056-30-3
NST-628 ( —— )
产品货号. M37591 CAS No. 3002056-30-3
NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2881 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称NST-628
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.
-
产品描述NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.
-
体外实验——
-
体内实验——
-
同义词——
-
通路MAPK/ERK Signaling
-
靶点Raf
-
受体Raf | MEK
-
研究领域——
-
适应症——
化学信息
-
CAS Number3002056-30-3
-
分子量488.46
-
分子式C22H18F2N4O5S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=C1OC=2C=C(OC3=NC=CC=C3F)C=CC2C(=C1CC=4C=CN=C(NS(=O)(=O)NC)C4F)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
R18
Antagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
-
NST-628
NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.
-
L-779450
L-779450 是一种有效的 ATP 竞争性 Raf 激酶抑制剂，IC50 为 10 nM。
