NSC45586
CAS No. 6300-44-3
NSC45586 ( —— )
产品货号. M24634 CAS No. 6300-44-3
NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥494 | 有现货 |
|
5MG | ¥786 | 有现货 |
|
10MG | ¥1158 | 有现货 |
|
25MG | ¥1968 | 有现货 |
|
50MG | ¥2940 | 有现货 |
|
100MG | ¥4682 | 有现货 |
|
500MG | ¥9963 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称NSC45586
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
-
产品描述NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体PHLPP1;PHLPP2
-
研究领域——
-
适应症——
化学信息
-
CAS Number6300-44-3
-
分子量413.4
-
分子式C20H18N6NaO3+
-
纯度>98% (HPLC)
-
溶解度DMSO:82 mg/mL;Water:Insoluble;Ethanol:Insoluble
-
SMILESCC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.