
5-methoxyflavone
CAS No. 42079-78-7
5-methoxyflavone ( —— )
产品货号. M18537 CAS No. 42079-78-7
5-甲氧基黄酮是一种天然存在的低分子量黄酮类化合物,具有广泛的生物活性。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥332 | 有现货 |
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50MG | ¥470 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称5-methoxyflavone
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述5-甲氧基黄酮是一种天然存在的低分子量黄酮类化合物,具有广泛的生物活性。
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产品描述5-methoxyflavone is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
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体外实验5-Methoxyflavone (compound 1) is identified as a candidate compound endowed with the ability to inhibit DNA pol-β in multiple and to prevent cell-cycle initiation and subsequent neuronal apoptosis in Aβ-challenged primary neuronal cultures. 5-methoxyflavone (10-30 μM) is able to significantly enhance toxicity of MMS on 92TAg cells. 5-Methoxyflavone (1 or 10 μM) significantly reduces polymerase activity on a gapped substrate. 5-Methoxyflavone (5-MF, 0-100 μg/mL) results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner.
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体内实验5-Methoxyflavone (100, 150 mg/kg, i.p) significantly decreases the latency time to loss of righting reflex. 5-Methoxyflavone (50, 100 and 150 mg/kg, i.p) exhibits a significant and dose-dependent reduction in the spontaneous locomotor activity. 5-Methoxyflavone (50, 100 mg/kg, i.p) reduces the rearing response. 5-Methoxyflavone (100, 125 and 150 mg/kg, i.p) completely abolishesed the grooming response similar to diazepam treated animals.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number42079-78-7
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分子量252.26
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分子式C16H12O3
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纯度>98% (HPLC)
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溶解度DMSO : 125 mg/mL 495.52 mM
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SMILESCOc1cccc2c1c(=O)cc(o2)c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. J. Org. Chem., 1993, 58 (27): 7903–7905.
产品手册




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