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NOSO-502
CAS No. 1894081-09-4
NOSO-502 ( NOSO502;NOSO 502 )
产品货号. M12974 CAS No. 1894081-09-4
NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NOSO-502
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation.
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产品描述NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation, has MIC values of 0.5-4 ug/ml against standard Enterobacteriaceae strains and carbapenem-resistant Enterobacteriaceae (CRE) isolates that produce KPC, AmpC, or OXA enzymes and metallo-β-lactamases; interacts strongly with a specific site on the 30S subunit of bacterial ribosomes but has no significant activity against any of the 55 cell surface receptors, transporters, or ion channels; NOSO-502 is active against a panel of Gram-positive and Gram-negative bacteria, including carbapenem-resistant and polymyxin-resistant strains, and exhibits promising in vivo activity in various murine infection models, a favorable in vitro safety profile, and a low potential for resistance development.
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同义词NOSO502;NOSO 502
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number1894081-09-4
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分子量1078.26
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分子式C47H80FN17O11
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纯度>98% (HPLC)
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溶解度——
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SMILESC1CC(N(C1)C(=O)C(CCCN)NC(=O)CNC(=O)C(CCN)NC(=O)C(C(CN)O)NC(=O)C(CCCCN)N)C(=O)NC(CC2=CC=CC=C2F)C(=O)NC(CCCCN)C(=O)NC(=CCCN=C(N)N)C(=O)O
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化学全称(Z)-2-((S)-6-amino-2-((S)-2-((S)-1-((2R,8S,11S,14S)-14,18-diamino-11-((S)-2-amino-1-hydroxyethyl)-8-(2-aminoethyl)-2-(3-aminopropyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecanoyl)pyrrolidine-2-carboxamido)-3-(2-fluorophenyl)propanamido)hexanamido)-5-gu
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Racine E, et al. Antimicrob Agents Chemother. 2018 Jul 9. pii: AAC.01016-18.
2. Zhao M, et al. Antimicrob Agents Chemother. 2018 Jul 9. pii: AAC.01067-18.
2. Zhao M, et al. Antimicrob Agents Chemother. 2018 Jul 9. pii: AAC.01067-18.
产品手册
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