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Delamanid

CAS No. 681492-22-8

Delamanid ( OPC67683;OPC-67683;OPC 67683 )

产品货号. M15601 CAS No. 681492-22-8

A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥316 有现货
10MG ¥518 有现货
25MG ¥1021 有现货
50MG ¥1823 有现货
100MG ¥2957 有现货
500MG ¥6926 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Delamanid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.
  • 产品描述
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB; shows MIC of 0.006-0.024 ug/mL in vitro and highly effective therapeutic activity at low doses in vivo.
  • 同义词
    OPC67683;OPC-67683;OPC 67683
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antifection
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    681492-22-8
  • 分子量
    534.48
  • 分子式
    C25H25F3N4O6
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 30 mg/mL
  • SMILES
    FC(F)(F)OC1=CC=C(OC2CCN(C3=CC=C(OC[C@@]4(C)CN5C(O4)=NC([N+]([O-])=O)=C5)C=C3)CC2)C=C1
  • 化学全称
    Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-, (2R)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Matsumoto M, et al. PLoS Med. 2006 Nov;3(11):e466.
2. Li X, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2256-62.
3. Hurdle JG, et al. J Antimicrob Chemother. 2008 Nov;62(5):1037-45.
产品手册
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