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NKY80

CAS No. 299442-43-6

NKY80 ( NKY 80;NKY-80 )

产品货号. M13924 CAS No. 299442-43-6

A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥316 有现货
5MG ¥502 有现货
10MG ¥786 有现货
25MG ¥1596 有现货
50MG ¥2778 有现货
100MG ¥4236 有现货
200MG ¥6099 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NKY80
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.
  • 产品描述
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively; displays little to no activity for other AC isoforms (IC50>100 uM); blocks both BAPTA-AM-stimulated cAMP formation and renin release in primary cultures of juxtaglomerular cells.
  • 同义词
    NKY 80;NKY-80
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Adenylate Cyclase
  • 受体
    Adenylate Cyclase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    299442-43-6
  • 分子量
    229.24
  • 分子式
    C12H11N3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1
  • 化学全称
    2-amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Onda T, et al. J Biol Chem. 2001 Dec 21;276(51):47785-93.
2. Ortiz-Capisano MC, et al. Hypertension. 2007 Mar;49(3):618-24.
3. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
产品手册
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