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NKP-608
CAS No. 177707-12-9
NKP-608 ( NK 608;NK608 )
产品货号. M12675 CAS No. 177707-12-9
A non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2098 | 有现货 |
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| 50MG | ￥8060 | 有现货 |
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| 100MG | ￥12798 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NKP-608
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM.
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产品描述A non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM; exhibits an anxiolytic-like effect in the social interaction and social exploration test in rats; orally active.Irritable Bowel Syndrome Discontinued
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同义词NK 608;NK608
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通路GPCR/G Protein
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靶点Neurokinin Receptor
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受体Neurokinin Receptor
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研究领域Other Indications
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适应症Irritable Bowel Syndrome
化学信息
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CAS Number177707-12-9
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分子量619.98
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分子式C31H24ClF6N3O2
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESO=C(C1=CC=NC2=CC=CC=C12)N[C@@H]3C[C@@H](CC4=CC=C(Cl)C=C4)N(C(C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O)CC3
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化学全称4-Quinolinecarboxamide, N-[(2R,4S)-1-[3,5-bis(trifluoromethyl)benzoyl]-2-[(4-chlorophenyl)methyl]-4-piperidinyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Gentsch C, et al. Behav Brain Res. 2002 Jul 18;133(2):363-8.
2. Vassout A, et al. Regul Pept. 2000 Dec 22;96(1-2):7-16.
3. Coulson FR, et al. Inflamm Res. 2002 Jul;51(7):317-23.
2. Vassout A, et al. Regul Pept. 2000 Dec 22;96(1-2):7-16.
3. Coulson FR, et al. Inflamm Res. 2002 Jul;51(7):317-23.
产品手册
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