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NITD-349

CAS No. 1473450-62-2

NITD-349 ( NITD349 )

产品货号. M12026 CAS No. 1473450-62-2

NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥365 有现货
5MG ¥583 有现货
10MG ¥988 有现货
25MG ¥1798 有现货
50MG ¥3013 有现货
100MG ¥4504 有现货
500MG ¥9882 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NITD-349
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
  • 产品描述
    NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
  • 同义词
    NITD349
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    1473450-62-2
  • 分子量
    306.36
  • 分子式
    C17H20F2N2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : ≥ 310 mg/mL 1011.91 mM
  • SMILES
    CC1(CCC(CC1)NC(=O)C2=CC3=C(N2)C=C(C=C3F)F)C
  • 化学全称
    N-(4,4-dimethylcyclohexyl)-4,6-difluoro-1H-indole-2-carboxamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168.
产品手册
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