021-51111890
购物车（）
sales@molnova.cn
NITD-349
CAS No. 1473450-62-2
NITD-349 ( NITD349 )
产品货号. M12026 CAS No. 1473450-62-2
NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥365 | 有现货 |
|
| 5MG | ￥583 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
|
| 25MG | ￥1798 | 有现货 |
|
| 50MG | ￥3013 | 有现货 |
|
| 100MG | ￥4504 | 有现货 |
|
| 500MG | ￥9882 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称NITD-349
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
-
产品描述NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
-
同义词NITD349
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Antibacterial
-
研究领域Infection
-
适应症——
化学信息
-
CAS Number1473450-62-2
-
分子量306.36
-
分子式C17H20F2N2O
-
纯度>98% (HPLC)
-
溶解度DMSO : ≥ 310 mg/mL 1011.91 mM
-
SMILESCC1(CCC(CC1)NC(=O)C2=CC3=C(N2)C=C(C=C3F)F)C
-
化学全称N-(4,4-dimethylcyclohexyl)-4,6-difluoro-1H-indole-2-carboxamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168.
产品手册
关联产品
-
Erythromycin
Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
-
Azlocillin sodium
Azlocillin is an acylampicillin with a broad spectrum against bacteria.
-
Tyrphostin AG 528
Tyrphostin AG 528 is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).
