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NIH-12848

CAS No. 959551-10-1

NIH-12848 ( NIH-12848;NCGC00012848-02. )

产品货号. M17694 CAS No. 959551-10-1

NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥437 有现货
5MG ¥689 有现货
10MG ¥988 有现货
25MG ¥1928 有现货
50MG ¥3394 有现货
100MG ¥4836 有现货
500MG ¥10368 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NIH-12848
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
  • 产品描述
    NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
  • 同义词
    NIH-12848;NCGC00012848-02.
  • 通路
    GPCR/G Protein
  • 靶点
    Neurokinin Receptor
  • 受体
    PI5P4Kγ
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    959551-10-1
  • 分子量
    385.41
  • 分子式
    C20H14F3N3S
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 28 mg/mL; 72.65 mM
  • SMILES
    FC(F)(F)c1ccccc1c1nc2ccccc2c(NCc2cccs2)n1
  • 化学全称
    N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Clarke JH,et al.Biochem J. 2015 Mar 1;466(2):359-67.
产品手册
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