NDI-091143 ( —— )

产品货号. M20771 CAS No. 2375840-87-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

NDI-091143
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay)indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
产品描述

NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay)indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
同义词

——
通路

Endocrinology/Hormones
靶点

ATPase
受体

ACLY
研究领域

Cancer
适应症

——

1.Jia Wei Silvana et al. An allosteric mechanism for potent inhibition of human ATP-citrate lyase[J]. Nature 2019.

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产品手册

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