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NDI-091143
CAS No. 2375840-87-0
NDI-091143 ( —— )
产品货号. M20771 CAS No. 2375840-87-0
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay)indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥324 | 有现货 |
|
| 5MG | ￥494 | 有现货 |
|
| 10MG | ￥818 | 有现货 |
|
| 25MG | ￥1677 | 有现货 |
|
| 50MG | ￥2989 | 有现货 |
|
| 100MG | ￥3191 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NDI-091143
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay)indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
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产品描述NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay)indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
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同义词——
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通路Endocrinology/Hormones
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靶点ATPase
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受体ACLY
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研究领域Cancer
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适应症——
化学信息
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CAS Number2375840-87-0
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分子量453.8
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分子式C20H14ClF2NO5S?
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纯度>98% (HPLC)
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溶解度DMSO:91 mg/mL (200.51 mM)
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SMILESCOC(=O)c1cc(Cl)c(O)c(S(=O)(=O)Nc2cc(-c3ccccc3)c(F)cc2F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Jia Wei Silvana et al. An allosteric mechanism for potent inhibition of human ATP-citrate lyase[J]. Nature 2019.
产品手册
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