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N-Acetyl-Calicheamicin

CAS No. 108212-76-6

N-Acetyl-Calicheamicin ( N-Acetyl-Calicheamicin γ;N-Acetyl-γ-calicheamicin )

产品货号. M10325 CAS No. 108212-76-6

N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥9153 有现货
10MG ¥12312 有现货
25MG ¥18225 有现货
50MG ¥24057 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    N-Acetyl-Calicheamicin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.
  • 产品描述
    N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission; a ADC payload in antibody drug conjugates development.
  • 同义词
    N-Acetyl-Calicheamicin γ;N-Acetyl-γ-calicheamicin
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    108212-76-6
  • 分子量
    1410.39
  • 分子式
    C57H76IN3O22S4
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    CCN(C1COC(CC1OC)OC2C(C(C(OC2OC3C#CC=CC#CC4(CC(=O)C(=C3C4=CCSSSC)NC(=O)OC)O)C)NOC5CC(C(C(O5)C)SC(=O)C6=C(C(=C(C(=C6OC)OC)OC7C(C(C(C(O7)C)O)OC)O)I)C)O)O)C(=O)C
  • 化学全称
    Carbamic acid, [(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyrano

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Stasi R, et al. Cancer Treat Rev. 2008 Feb;34(1):49-60.
2. Naito K, et al. Leukemia. 2000 Aug;14(8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96.
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