Mibampator

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Mibampator 是一种有效的选择性 AMPA 受体增强剂。

Mibampator is an effective and selective AMPA receptor potentiator.(In Vivo):Mibampator reverses the central effects of an acutely intoxicating dose of ethanol in rats. Mibampator dose-dependently reverses ethanol-induced deficits in both motor coordination and disruptions in an operant task in the food reward test.

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Incubation of Mibampator (LY451395) with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies of the preclinical species . LY404187 and Mibampator (LY451395) reverses the central effects of an acutely intoxicating dose of ethanol in the rat. Mibampator (LY451395) significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward .

LY451395

Membrane Transporter/Ion Channel

iGluR

Human Endogenous Metabolite

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375345-95-2

438.6

C21H30N2O4S2

>98% (HPLC)

In Vitro:?DMSO : ≥ 25 mg/mL (57.00 mM)

CC(C)S(=O)(=O)NC[C@H](C)c1ccc(cc1)-c1ccc(CCNS(C)(=O)=O)cc1

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(-20℃)

With Ice Pack

≥ 2 years