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MLE-4901
CAS No. 941690-55-7
MLE-4901 ( MLE4901;AZD-2624;AZD2624;Pavinetant )
产品货号. M16736 CAS No. 941690-55-7
A potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of schizophrenia.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MLE-4901
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of schizophrenia.
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产品描述A potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of schizophrenia; demonstrates drug-like properties with low metabolic turnover rate in vitro and moderate human plasma protein binding.Schizophrenia Phase 2 Discontinued
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同义词MLE4901;AZD-2624;AZD2624;Pavinetant
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通路GPCR/G Protein
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靶点Neurokinin Receptor
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受体Neurokinin Receptor
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研究领域Neurological Disease
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适应症Schizophrenia
化学信息
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CAS Number941690-55-7
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分子量459.56
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分子式C26H25N3O3S
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 50 mg/mL 108.80 mM; H2O : < 0.1 mg/mL
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SMILESO=C(C1=C(NS(=O)(C)=O)C(C2=CC=CC=C2)=NC3=CC=CC=C13)N[C@H](C4=CC=CC=C4)CC
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化学全称(S)-3-(methylsulfonamido)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Li Y, et al. Xenobiotica. 2010 Nov;40(11):721-9.
2. Skorupskaite K, et al. Neuroendocrinology. 2017 Apr 5. doi: 10.1159/000473893.
3. Prague JK, et al. Lancet. 2017 May 6;389(10081):1809-1820.
2. Skorupskaite K, et al. Neuroendocrinology. 2017 Apr 5. doi: 10.1159/000473893.
3. Prague JK, et al. Lancet. 2017 May 6;389(10081):1809-1820.
产品手册
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