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MID-1
CAS No. 312608-54-1
MID-1 ( —— )
产品货号. M22748 CAS No. 312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1320 | 有现货 |
|
| 10MG | ￥2001 | 有现货 |
|
| 25MG | ￥3686 | 有现货 |
|
| 50MG | ￥5443 | 有现货 |
|
| 100MG | ￥7744 | 有现货 |
|
| 500MG | ￥15552 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MID-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
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产品描述MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
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同义词——
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通路Others
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靶点Other Targets
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受体MG53-IRS-1
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研究领域——
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适应症——
化学信息
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CAS Number312608-54-1
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分子量293.3
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分子式C12H11N3O4S
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纯度>98% (HPLC)
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溶解度DMSO:31.25 mg/mL?(106.55 mM;?Need ultrasonic)
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SMILESCCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
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