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首页- Products - Others - Other Targets - MID-1

MID-1

CAS No. 312608-54-1

MID-1 ( —— )

产品货号. M22748 CAS No. 312608-54-1

MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ￥1320 有现货
10MG ￥2001 有现货
25MG ￥3686 有现货
50MG ￥5443 有现货
100MG ￥7744 有现货
500MG ￥15552 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    MID-1
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
  • 产品描述
    MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    MG53-IRS-1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    312608-54-1
  • 分子量
    293.3
  • 分子式
    C12H11N3O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:31.25 mg/mL?(106.55 mM;?Need ultrasonic)
  • SMILES
    CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
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