IL-8 Inhibitor

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Antileukinate 是一种六肽，是有效的 CXC 趋化因子受体 (CXCR) 抑制剂。Antileukinate 能抑制中性粒细胞趋化和活化。Antileukinate 可用于急性炎症和损伤的研究。

Antileukinate, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury.

Antileukinate (52.63 mg/kg; s.c.) protectes mice against acute pancreatitis and associated lung injury.Antileukinate (5mg/kg; s.c.) inhibits the interaction between murine eotaxin and murine eosinophil.Animal Model:Swiss mice (20-25g)Dosage:52.63 mg/kg Administration:Subcutaneous injectionResult:Reduced pancreatic edema induced by Caerulein (50 μg/kg).

Antileukinate inhibits the binding of human eotaxin to human eosinophils with an IC50 of 8.2 μM.Antileukinate (10-100 μM; 2 hours) significantly suppresses eosinophil chemotaxis to human eotaxin.

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Others

Other Targets

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138559-60-1

1003.2

C45H66N18O7S

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years