Yadanzigan (YDZG) is an anti-inflammatory agent and a NLRP3 inhibitor. Yadanzigan specifically inhibits NLRP3 activation via inhibiting NF-κB pathway and Reactive Oxygen Species production. Yadanzigan also moderates LPS -induced acute lung injury (ALI) in mice.

UM4118 (N-quinolin-8-ylpyridine-2-carboxamide) is a copper ion carrier that triggers an atypical form of mitochondria-based cell death (cuproptosis).UM4118 can be used for the study of acute myeloid leukemia.UM4118 showed no significant effect on VEGF and b-FGF stimulated HMVEC proliferation with LC values of 0.013 and 0.018 μM, respectively.

[Ala1]-PAR-4 (1-6) (mouse)