Potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.

TAT-amide TFA is a cell penetrating peptide. The cell - penetrating peptides (CPPs) is a kind of access to the short amino acid sequence of different cells.

Bicuculline methiodide 是一种有效的 GABA(A) 受体阻断剂。Bicuculline methiodide 改变膜特性和放电模式。Bicuculline methiodide 降低 Apamin 敏感性后超极化，而 Apamin 是从蜂毒中分离到毒素，能够阻断小电导 Ca2+ 激活的 K+ 通道素。Bicuculline methiodide 通过阻断对 Apamin 敏感的 Ca2+ 激活的 K+ 电流促进爆发性放电。