Thalidomide-O-amido-C6-NH2 TFA ( Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA )

产品货号. M26948 CAS No. 1950635-14-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Thalidomide-O-amido-C6-NH2 TFA
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

沙利度胺-O-酰胺基-C6-NH2 TFA，一种合成的 E3 连接酶配体-接头缀合物，含有基于沙利度胺的 cereblon 配体和接头。
产品描述

Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

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同义词

Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA
通路

Others
靶点

Other Targets
受体

DNA replication| HCMV| Nucleoside Analogue
研究领域

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适应症

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1.Hamada A, et al. Clinical pharmacokinetics of cytarabine formulations.Clin Pharmacokinet. 2002;41(10):705-18.

计算器

产品手册

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