MDCG sodium ( —— )

产品货号. M36562 CAS No. 91840-27-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

MDCG sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

N-methyl-N-dithiocarboxyglucamine (MDCG) sodium 在小鼠模型中动员并促进金属硫蛋白结合 109Cd 的排泄。N-methyl-N-dithiocarboxyglucamine 显著降低肝脏和肾脏的镉含量，而肝脏和肾脏是最易受镉诱导的毒性影响的器官。
产品描述

N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity.
体外实验

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体内实验

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同义词

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通路

Proteasome/Ubiquitin
靶点

Endogenous Metabolite
受体

Endogenous Metabolite
研究领域

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适应症

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1. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.?

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