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5-Aminovaleric acid

CAS No. 660-88-8

5-Aminovaleric acid ( —— )

产品货号. M19658 CAS No. 660-88-8

5-氨基戊酸(或5-氨基戊酸)是赖氨酸降解产物。它可以内源产生,也可以通过赖氨酸的细菌分解代谢产生。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG 获取报价 有现货
1G ¥222 有现货

生物学信息

  • 产品名称
    5-Aminovaleric acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    5-氨基戊酸(或5-氨基戊酸)是赖氨酸降解产物。它可以内源产生,也可以通过赖氨酸的细菌分解代谢产生。
  • 产品描述
    5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction: L-lysine leads to cadverine leads to L-piperideine leads 5-aminovalerate . In other words it is a metabolite of cadaverine which is formed via the intermediate 1-piperideine. Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue. High levels of 5-aminovalerate in biofluids may indicate bacterial overgrowth or endogenous tissue necrosis. In most cases endogenous 5-aminovalerate is thought to be primarily a microbial metabolite produced by the gut or oral microflora although it can be produced endogenously. 5-aminopentanoic acid is an in vivo substrate of 4-aminobutyrate:2-oxoglutarate aminotransferase .
  • 体外实验
    5-Aminovaleric acid is a normal metabolite present in human saliva, with a tendency to elevated concentration in patients with chronic periodontitis. 5-Aminovaleric acid is also believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.It is also known as an antifibrinolytic amino acid analog and so it functions as a weak inhibitor of the blood clotting pathway.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    Endogenous Metabolite
  • 受体
    others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    660-88-8
  • 分子量
    117.15
  • 分子式
    C5H11NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    NCCCCC(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Santos A Zanetta S Cresteil T et al. Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans[J]. Clinical Cancer Research 2000 6(5):2012-2020.
产品手册
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