Protonstatin-1
CAS No. 521972-99-6
Protonstatin-1 ( —— )
产品货号. M36384 CAS No. 521972-99-6
Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥2261 | 有现货 |
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| 10MG | ¥3306 | 有现货 |
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| 25MG | ¥5171 | 有现货 |
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| 50MG | ¥7031 | 有现货 |
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| 100MG | ¥8883 | 有现货 |
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| 200MG | ¥12330 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥2356 | 有现货 |
|
生物学信息
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产品名称Protonstatin-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
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产品描述Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
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体外实验——
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体内实验——
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同义词——
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通路Angiogenesis
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靶点IGF-1R
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受体IGF-1R
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研究领域——
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适应症——
化学信息
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CAS Number521972-99-6
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分子量211.26
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分子式C8H5NO2S2
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C1NC(=S)S\C1=C/C1=CC=CO1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Ganitumab
Ganitumab (AMG 479) 是一种重组人1型胰岛素样生长因子受体 (IGF1R) 单克隆抗体。Ganitumab 识别具有亚纳米摩尔亲和力的小鼠 IGF1R (KD=0.22 nM),并抑制小鼠 IGF1R 与 IGF1 和 IGF2 的相互作用。Ganitumab 可用于癌症研究。
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GSK1904529A
GSK1904529A 是 IGF-1R 和 IR 的选择性抑制剂,IC50 分别为 27 nM 和 25 nM。
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KW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
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