Neuropeptide FF receptor agonist (Ki values are 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). Potentiates the antinociceptive action of morphine in vivo and reverses the loss of morphine potency in tolerant animals. Also increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) (EC50 ~ 50 μM).

Selvigaltin (GB1211) 是一种具有口服活性的 galectin-3 (Gal-3) 抑制剂。

CGP71683 是一种竞争性神经肽 Y5 受体拮抗剂 (Ki: 1.3 nM)，对细胞膜中的 Y1 受体 (Ki >4000 nM) 和 Y2 受体 (Ki: 200 nM) 无明显活性。