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RFRP-1 (human)
CAS No. 311309-25-8
RFRP-1 (human) ( —— )
产品货号. M30817 CAS No. 311309-25-8
Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2480 | 有现货 |
|
| 10MG | ￥4408 | 有现货 |
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| 25MG | ￥7384 | 有现货 |
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| 50MG | ￥11067 | 有现货 |
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| 100MG | ￥16290 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称RFRP-1 (human)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
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产品描述Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
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体外实验——
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体内实验RFRP-1(human) rapidly and reversibly decreases shortening and relaxation in isolated mammalian cardiac myocytes in a dose dependent manner.Intravenous injection of RFRP-1(human) in mice decreases heart rate, stroke volume, ejection fraction, and cardiac output.
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同义词——
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通路GPCR/G Protein
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靶点Neuropeptide Y Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number311309-25-8
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分子量1428.72
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分子式C67H101N19O14S
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 100 mg/mL (69.99 mM)
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SMILES[H]N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Galanin Receptor Lig...
The chimeric peptide M35 [galanin (1-13)-bradykinin(2-9) amide] is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. The radiolabelled M35 and performed equilibrium binding studies with [125I] M35 on the rat pancreatic beta-cell line Rin m 5F.
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Galanin (1-30), huma...
Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM. Endogenous peptide with multiple endocrine, metabolic and behavioral effects. Has been shown to have an action on intestinal smooth muscle, insulin and somatostatin release, and synaptic neurotransmission.
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Neuropeptide FF
Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
