Galnon ( —— )

产品货号. M22086 CAS No. 475115-35-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Galnon
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Galnon 是一种甘丙肽受体激动剂，可改善皮质骨组织的内在特性 Galnon 的特点是抑制癫痫发作、减少进食行为、减少阿片戒断的体征，并减轻对部分坐骨神经损伤的热痛觉过敏反应。
产品描述

Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue propertiesGalnon has been characterized to inhibit seizures, decrease feeding behaviour, diminish physical signs of opiate withdrawal and to alleviate heat-hyperalgesic response to partial sciatic nerve injury[1]. Galnon, a GAL receptor agonist, may enhance osteoclastic bone resorption in OVX rats. Although galnon reduced bone volume, biomechanical testing revealed that bone of galnon-treated animals was mechanically superior per unit area. Taken together, galnon simultaneously improves the intrinsic quality of cortical bone whilst stimulating osteoclastic activity in the OVX rat model.
体外实验

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体内实验

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同义词

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通路

GPCR/G Protein
靶点

Neuropeptide Y Receptor
受体

Galanin receptor
研究领域

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适应症

——

CAS Number

475115-35-6
分子量

678.83
分子式

C40H46N4O6
纯度

>98% (HPLC)
溶解度

——
SMILES

Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc34)ccc12
化学全称

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1. Sollenberg U , Bartfai T , Langel U . Galnon - A low-molecular weight ligand of the galanin receptors[J]. Neuropeptides, 2005, 39(3):161-163.

计算器

产品手册

关联产品

Neuropeptide Y (22-3...

Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian central nervous system, which consists of the brain and spinal cord. It is secreted alongside other neurotransmitters such as GABA and glutamate.
GALNON TFA(475115-35...

Galnon 是一种新型非肽甘丙肽受体激动剂（GAL1 和 GAL2 Ki 分别为 11.7 和 34.1 μM）。
Neuropeptide FF

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).