Galnon ( —— )

产品货号. M22086 CAS No. 475115-35-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Galnon
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Galnon 是一种甘丙肽受体激动剂，可改善皮质骨组织的内在特性 Galnon 的特点是抑制癫痫发作、减少进食行为、减少阿片戒断的体征，并减轻对部分坐骨神经损伤的热痛觉过敏反应。
产品描述

Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue propertiesGalnon has been characterized to inhibit seizures, decrease feeding behaviour, diminish physical signs of opiate withdrawal and to alleviate heat-hyperalgesic response to partial sciatic nerve injury[1]. Galnon, a GAL receptor agonist, may enhance osteoclastic bone resorption in OVX rats. Although galnon reduced bone volume, biomechanical testing revealed that bone of galnon-treated animals was mechanically superior per unit area. Taken together, galnon simultaneously improves the intrinsic quality of cortical bone whilst stimulating osteoclastic activity in the OVX rat model.
体外实验

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体内实验

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同义词

——
通路

GPCR/G Protein
靶点

Neuropeptide Y Receptor
受体

Galanin receptor
研究领域

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适应症

——

CAS Number

475115-35-6
分子量

678.83
分子式

C40H46N4O6
纯度

>98% (HPLC)
溶解度

——
SMILES

Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc34)ccc12
化学全称

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1. Sollenberg U , Bartfai T , Langel U . Galnon - A low-molecular weight ligand of the galanin receptors[J]. Neuropeptides, 2005, 39(3):161-163.

计算器

产品手册

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