IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein disease, polyglutamine and polyalanine diseases, leukodystrophy, cystic fibrosis, multiple sclerosis, lysosome storage disorders, amyloidosis diseases, inflammation, metabolic disorders, cardiovascular diseases, osteoporosis, neurological trauma, and more.

羽扇豆酮是从芭蕉中分离出来的天然产物，具有良好的抗糖尿病活性，并具有抗炎活性。羽扇豆酮是有效的 PTP1B 抑制剂，IC50 值为 15.11±1.23μM。

3α-Aminocholestane 是含有选择性 SH2 结构域的肌醇-5'-磷酸酶 1 (SHIP1) 的抑制剂，其 IC50值约为 2.5 μM。