IL-4-inhibitor-1 ( —— )

产品货号. M34855 CAS No. 1332184-63-0

COA

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HNMR

HPLC

MSDS

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产品名称

IL-4-inhibitor-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

IL-4-inhibitor-1 (compound 52) 是IL-4 的抑制剂，其 EC50 值为 1.81 μM。
产品描述

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 μM.
体外实验

IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context.IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC50 value of 3.1 μM, but did not affect the levels of STAT-6.
体内实验

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同义词

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通路

Apoptosis
靶点

IL Receptor
受体

IL Receptor
研究领域

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适应症

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1. Sean P Quinnell, et al. A Small-Molecule Inhibitor to the Cytokine Interleukin-4. ACS Chem Biol. 2020 Oct 16;15(10):2649-2654.?

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