021-51111890
购物车（）
sales@molnova.cn
GW438014A
CAS No. 469861-49-2
GW438014A ( —— )
产品货号. M33987 CAS No. 469861-49-2
GW438014A 是一种有效的选择性 NPY-Y5 受体拮抗剂。GW438014A 抑制食物摄入并减少肥胖啮齿动物的体重增加。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥328 | 有现货 |
|
| 10MG | ￥525 | 有现货 |
|
| 25MG | ￥1032 | 有现货 |
|
| 50MG | ￥1609 | 有现货 |
|
| 100MG | ￥2232 | 有现货 |
|
| 200MG | ￥3051 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称GW438014A
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述GW438014A 是一种有效的选择性 NPY-Y5 受体拮抗剂。GW438014A 抑制食物摄入并减少肥胖啮齿动物的体重增加。
-
产品描述GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.
-
体外实验——
-
体内实验Animal Model:obese ob/ob mice Dosage:10 mg/kg Administration:intraperitoneal injection; daily, for 7 d Result:Decreased the rate of weight gain in both lean and obese rats.
-
同义词——
-
通路GPCR/G Protein
-
靶点Neuropeptide Y Receptor
-
受体Neuropeptide Y Receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number469861-49-2
-
分子量437.51
-
分子式C23H23N3O4S
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : 250 mg/mL (571.42 mM; 超声助溶 )
-
SMILESO=C(NC1=NC=2C=CC=CC2N1CCC=3C=CC=CC3)C=4C=CC=CC4.O=S(=O)(O)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Daniels AJ, et, al. Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist. Regul Pept. 2002 Jun 15;106(1-3):47-54.?
产品手册
关联产品
-
Velneperit
Velneperit 是一种有效的选择性神经肽 Y (NPY) Y5 受体，正在评估其治疗肥胖的效果。
-
[Leu31,Pro34]-Neurop...
High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
-
Neuropeptide SF (mou...
Neuropeptide FF receptor agonist (Ki values are 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). Potentiates the antinociceptive action of morphine in vivo and reverses the loss of morphine potency in tolerant animals. Also increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) (EC50 ~ 50 μM).
